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用间接方法测定给予马来酸乙酰丙嗪的犬的血压。

Determination of blood pressure by indirect methods in dogs given acetylpromazine maleate.

作者信息

Coulter D B, Whelan S C, Wilson R C, Goetsch D D

出版信息

Cornell Vet. 1981 Jan;71(1):75-84.

PMID:7226849
Abstract

This study was designed to monitor and compare indirect blood pressures by two methods (ultrasonic Doppler and photoelectric) after intravenous acetylpromazine maleate at three different doses (0.11, 0.55, and 1.10 mg/kg). Sixteen unanesthetized dogs were placed in right lateral recumbency and pressures estimated from the left hind leg at two preinjection times and at 3, 15, 60 and 120 minutes postinjection. This procedure was followed for each dog for each of the three doses. Preinjection ultrasonic mean values and standard deviations were similar to published values. Photoelectric systolic pressures were lower and diastolic pressures higher than ultrasonic systolic and diastolic pressures. The decrease in blood pressure was detected by both methods. Neither method revealed a dose related response.

摘要

本研究旨在监测和比较静脉注射三种不同剂量(0.11、0.55和1.10mg/kg)马来酸乙酰丙嗪后,通过两种方法(超声多普勒法和光电法)测量的间接血压。16只未麻醉的狗被置于右侧卧位,在注射前的两个时间点以及注射后3、15、60和120分钟从左后腿估计血压。对每只狗的三种剂量都进行了此操作。注射前超声测量的平均值和标准差与已发表的值相似。光电法测量的收缩压低于超声法,舒张压高于超声法。两种方法均检测到血压下降。两种方法均未显示出剂量相关反应。

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