Plachetka J R, Larson D F, Salomon N W, Copeland J G
Crit Care Med. 1981 Jun;9(6):487-9. doi: 10.1097/00003246-198106000-00011.
The authors used an in vitro flow system to evaluate the sources of error in a previously described closed system thermodilution method for cardiac output determinations. Cardiac outputs were overestimated by as much as 49% because the injectate warmed as it was drawn through the connecting tubing. Submerging the tubing in the ice bath prevented this problem. The authors also evaluated a new closed system thermodilution cardiac output method. The method employed a bypass line and a spring loaded autosyringe which enables the user to flush the system with cold fluid, thereby ensuring accurate injectate temperatures. Cardiac output determinations with this method were as accurate as those obtained with a CO2 powered injector. Additionally, this method is easy to use, accommodates injection volumes of 1-10 ml, and is inexpensive.
作者使用体外流动系统评估了先前描述的用于心输出量测定的封闭系统热稀释法中的误差来源。由于注入液在通过连接管抽取时升温，心输出量被高估了多达49%。将连接管浸入冰浴可防止此问题。作者还评估了一种新的封闭系统热稀释心输出量测定方法。该方法采用了一条旁路线和一个弹簧加载自动注射器，可使用户用冷流体冲洗系统，从而确保注入液温度准确。用此方法测定的心输出量与用二氧化碳驱动注射器获得的结果一样准确。此外，该方法易于使用，可容纳1至10毫升的注射量，且成本低廉。
