Dorn M R, Walker B K
Chest. 1981 Apr;79(4):482-3. doi: 10.1378/chest.79.4.482.
We describe a patient with the sudden onset of pulmonary edema on two separate occasions immediately after the ingestion of hydrochlorothiazide. Although this adverse reaction to hydrochlorothiazide has been reported previously in six patients, the cause of the pulmonary sensitivity remains obscure. A noncardiogenic etiology has been suggested, but prior cases have failed to document cardiopulmonary hemodynamic measurements. A Swan-Ganz balloon flotation catheter demonstrated cardiopulmonary pressures in our patient consistent with a noncardiac origin of the pulmonary edema.
我们描述了一名患者，在服用氢氯噻嗪后立即在两个不同场合突然出现肺水肿。尽管先前已有6例患者报告过这种氢氯噻嗪的不良反应，但肺部敏感性的原因仍不清楚。有人提出了非心源性病因，但之前的病例未能记录心肺血流动力学测量结果。一根Swan-Ganz气囊漂浮导管显示，我们患者的心肺压力与肺水肿的非心脏起源一致。
