Frierson J H, Marvel S L, Thomas G M
Department of Medicine, Salem Hospital, Oregon, USA.
Clin Cardiol. 1995 Feb;18(2):112-4. doi: 10.1002/clc.4960180215.
A 73-year-old woman presented with acute pulmonary edema and hypotension less than 1 h after taking hydrochlorothiazide 50 mg, a reaction which has been reported as a rare but classic adverse drug response. Though prior cases have supported a noncardiogenic pulmonary edema syndrome, hemodynamic monitoring in this patient demonstrated a refractory low cardiac output state for more than 24 h. In the absence of other etiologies, this represents a new finding.
一名73岁女性在服用50毫克氢氯噻嗪后不到1小时出现急性肺水肿和低血压，这种反应已被报道为一种罕见但典型的药物不良反应。尽管先前的病例支持非心源性肺水肿综合征，但该患者的血流动力学监测显示难治性低心输出量状态持续超过24小时。在没有其他病因的情况下，这是一个新发现。
