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高渗性脱水时血钠水平的控制性下降：可能避免补液性惊厥。

Controlled fall in natremia in hypertonic dehydration: possible avoidance of rehydration seizures.

作者信息

Kahn A, Blum D, Casimir G, Brachet E

出版信息

Eur J Pediatr. 1981 Feb;135(3):293-6. doi: 10.1007/BF00442106.

DOI:10.1007/BF00442106
PMID:7227384
Abstract

This prospective study comprises 40 infants with severe hypernatremic dehydration due to gastroenteritis. During the first 24h, natremia was closely monitored and infusion rates were adjusted so as to keep the rate of fall in natremia below 0.5 mEq/l/h. This could be achieved by giving a 70 mEq/l Na solution at the rate of 120 ml/kg/24 h. Rehydration was uneventful in all cases, and no convulsions were observed.

摘要

这项前瞻性研究纳入了40例因肠胃炎导致严重高钠血症脱水的婴儿。在最初24小时内，密切监测血钠水平并调整输液速度，以使血钠下降速度低于0.5毫当量/升/小时。这可以通过以120毫升/千克/24小时的速度输注70毫当量/升的钠溶液来实现。所有病例补液过程均顺利，未观察到惊厥发作。

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Controlled fall in natremia and risk of seizures in hypertonic dehydration.
Intensive Care Med. 1979 Mar;5(1):27-31. doi: 10.1007/BF01738999.