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婴儿高钠血症性脱水的治疗

Treatment of hypernatraemic dehydration in infancy.

作者信息

Banister A, Matin-Siddiqi S A, Hatcher G W

出版信息

Arch Dis Child. 1975 Mar;50(3):179-86. doi: 10.1136/adc.50.3.179.

Abstract

Thirty-eight infants with severe hyperosmolar dehydration and hypernatraemia were treated, using three regimens of intravenous fluids: A. 1/2 normal saline, given fast; B.1/2 normal saline given slowly; C. 1/5 normal saline. 28 of the infants were studied in a treatment trial, and it is concluded tha 0-18% saline in 4-3% dextrose, with the early addition of potassium given at a rate of 100 ml/kg estimated rehydrated weight per 24 hours gives satisfactory rehydration within 48 hours, with little risk of convulsions.

摘要

对38例患有严重高渗性脱水和高钠血症的婴儿采用三种静脉补液方案进行治疗:A. 快速输注1/2生理盐水;B. 缓慢输注1/2生理盐水;C. 1/5生理盐水。对其中28例婴儿进行了治疗试验,得出的结论是,4% - 3%葡萄糖溶液中加入0 - 18%生理盐水,并早期以每24小时每千克估计补液体重100毫升的速率添加钾,可在48小时内实现满意的补液效果,惊厥风险很小。

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本文引用的文献

1
Correlation between RBC osmotic fragility and serum sodium.红细胞渗透脆性与血清钠之间的相关性。
Am J Dis Child. 1962 Sep;104:281-8. doi: 10.1001/archpedi.1962.02080030283011.
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HYPERTONIC DEHYDRATION.高渗性脱水
N Y State J Med. 1964 Sep 1;64:2157-60.
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Hypernatremia accompanying infant diarrhea.
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Warning regarding administration of fluids.关于液体给药的警告。
Clin Pediatr (Phila). 1967 Jun;6(6):323. doi: 10.1177/000992286700600604.

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