Ayoola E A
Gastrointest Endosc. 1981 May;27(2):60-2. doi: 10.1016/s0016-5107(81)73150-x.
In Nigeria, where the carrier rate of hepatitis B antigen (HBsAg) is between 5 and 10%, it must be assumed that the instrument used for upper gastrointestinal endoscopy has had contact with an HBsAg-positive patient. The risk of type B hepatitis transmission via upper gastrointestinal endoscopy was evaluated, therefore, in 61 patients who were followed for 1 year after the procedure. Four of these patients were "carriers" of HBsAg. None of the study group developed jaundice or hepatomegaly during the follow-up period. In 21 patients, serial liver function tests and screening for HBsAg were obtained. None of the 19 seronegative patients developed abnormal liver function tests or converted to HBsAg-positive. It is concluded that, while transmission of HBsAg is theoretically possible, the risk appears minimal. HBsAg positivity should not be a contraindication, therefore, in patients who need endoscopic assessment for definitive management.
在尼日利亚，乙肝抗原（HBsAg）携带率在5%至10%之间，因此必须假定用于上消化道内镜检查的器械曾接触过HBsAg阳性患者。为此，对61例接受该手术后随访1年的患者评估了经上消化道内镜检查传播乙型肝炎的风险。这些患者中有4例是HBsAg“携带者”。在随访期间，研究组中没有患者出现黄疸或肝肿大。对21例患者进行了系列肝功能检查和HBsAg筛查。19例血清阴性患者中没有出现肝功能检查异常或转为HBsAg阳性。结论是，虽然理论上可能传播HBsAg，但风险似乎极小。因此，HBsAg阳性不应成为需要进行内镜评估以明确治疗的患者的禁忌证。
