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心绞痛患者的血液粘度、红细胞柔韧性、血细胞比容和血浆纤维蛋白原

Blood viscosity, red-cell flexibility, haematocrit, and plasma-fibrinogen in patients with angina.

作者信息

Nicolaides A N, Horbourne T, Bowers R, Kidner P H, Besterman E M

出版信息

Lancet. 1977 Nov 5;2(8045):943-5. doi: 10.1016/s0140-6736(77)90886-8.

DOI:10.1016/s0140-6736(77)90886-8
PMID:72287
Abstract

Whole-blood viscosity, haematocrit and plasma-fibrinogen concentration were measured in 22 patients with angina and 22 controls. All four variables were significantly higher in patients with angina. When the viscosity was corrected to a standard haematocrit (45%), however, there was no significant difference in the mean viscosity of the two groups, indicating that the higher viscosity in patients with angina is the result of the higher haematocrit. Increased red-cell flexibility tends to counteract the effect of increased plasma-fibrinogen concentration, which tends to increase blood-viscosity.

摘要

对22例心绞痛患者和22例对照者测量了全血粘度、血细胞比容和血浆纤维蛋白原浓度。所有这四个变量在心绞痛患者中均显著更高。然而,当将粘度校正至标准血细胞比容(45%)时,两组的平均粘度没有显著差异,这表明心绞痛患者较高的粘度是血细胞比容较高的结果。红细胞柔韧性增加往往会抵消血浆纤维蛋白原浓度增加的影响,而血浆纤维蛋白原浓度增加往往会使血液粘度升高。

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Blood viscosity, red-cell flexibility, haematocrit, and plasma-fibrinogen in patients with angina.心绞痛患者的血液粘度、红细胞柔韧性、血细胞比容和血浆纤维蛋白原
Lancet. 1977 Nov 5;2(8045):943-5. doi: 10.1016/s0140-6736(77)90886-8.
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