心肌梗死后红细胞变形能力及其他血液流变学变量的变化。
Changes in red cell deformability and other haemorrheological variables after myocardial infarction.
作者信息
Dodds A J, Boyd M J, Allen J, Bennett E D, Flute P T, Dormandy J A
出版信息
Br Heart J. 1980 Nov;44(5):508-11. doi: 10.1136/hrt.44.5.508.
Abstract
Haemorrheological variables were studied in 43 patients after acute myocardial infarction. Red cell deformability, by a filtration method, was significantly lower within 12 hours of infarction than subsequently. This drop was greater in the presence of haemodynamic complications. Blood viscosity, particularly when adjusted to a standard haematocrit, rose in the week after infarction, as did plasma viscosity and plasma fibrinogen. Haematocrit, however, fell over this period. These changes could increase myocardial ischaemia and lead to extension of the area of infarction.
摘要
对43例急性心肌梗死后的患者进行了血液流变学变量研究。通过过滤法测得的红细胞变形能力在梗死12小时内显著低于随后时期。在存在血流动力学并发症时，这种下降更为明显。血液粘度，特别是在调整到标准血细胞比容时，在梗死后一周上升，血浆粘度和血浆纤维蛋白原也是如此。然而，血细胞比容在此期间下降。这些变化可能会增加心肌缺血并导致梗死面积扩大。
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