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帕金森病患者的视觉和听觉诱发电位

Visual and auditory evoked responses in patients with Parkinson's disease.

作者信息

Gawel M J, Das P, Vincent S, Rose F C

出版信息

J Neurol Neurosurg Psychiatry. 1981 Mar;44(3):227-32. doi: 10.1136/jnnp.44.3.227.

DOI:10.1136/jnnp.44.3.227
PMID:7229646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC490897/
Abstract

Visual evoked responses were obtained in 47 Parkinsonian patients and 26 age-matched controls. The stimulation to binocular and uniocular latency of the major positive peak was longer in the Parkinsonian patients and its amplitude was smaller than in the control subjects. There was a large interocular difference suggesting that at least part of the delay occurs at prechiasmatic level. The latency and amplitude varied markedly following ingestion of levodopa as Sinemet. Auditory evoked potentials were obtained in 16 Parkinsonian patients and 11 age-matched controls. The latency of the NV wave was prolonged in the former although the amplitude was the same, suggesting that the abnormality may be a widespread one.

摘要

对47例帕金森病患者和26例年龄匹配的对照者进行了视觉诱发电位检测。帕金森病患者主要正峰的双眼和单眼刺激潜伏期较长,其波幅小于对照者。两眼间差异很大,提示至少部分延迟发生在视交叉前水平。服用左旋多巴(息宁)后,潜伏期和波幅有明显变化。对16例帕金森病患者和11例年龄匹配的对照者进行了听觉诱发电位检测。虽然波幅相同,但前者NⅤ波潜伏期延长,提示异常可能较为广泛。

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