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[使用皮内试验诊断囊尾蚴病]

[Diagnosis of cysticercosis using the intradermal test].

作者信息

Zapart W, Ptasiński J, Pastuszko M, Ostrowski K, Bogusz R

出版信息

Angew Parasitol. 1981 Feb;22(1):21-5.

PMID:7235288
Abstract

56 healthy rabbits were inoculated with the active Cysticercus each into lateral ventricle of the brain, the white substance of the brain and into Spatium subarachnoideale. Rabbits were killed after 32 weeks p.i. Then their brains were macro- ev. microscopically investigated. The positive seroreactions (ringpreciptitation reaction and the latex-test) were observed at the beginning of the second week after infection. Curve of the titers was revealed two tops: first one between 6-7 weeks, second one 16-22 weeks after infection. All rabbits except one reacted positive on the application of the Cysticercus antigen. The control group consisted of the 8 rabbits revealed negative serological and immunological reactions. Three groups of the cerebral cysticercosis, dependent on the localization of the cysticerci in the brains, were observed: oedema form, hydrocephalous form and tumor form. These forms as well as the symptoms are similar to the human cerebral cysticercosis.

摘要

将56只健康兔子分别接种活囊尾蚴于脑侧脑室、脑白质和蛛网膜下腔。接种后32周处死兔子,然后对其大脑进行大体及显微镜检查。感染后第二周开始观察到阳性血清反应(环状沉淀反应和乳胶试验)。滴度曲线显示有两个峰值:第一个在感染后6 - 7周,第二个在感染后16 - 22周。除1只兔子外,所有兔子应用囊尾蚴抗原后反应均为阳性。对照组由8只兔子组成,其血清学和免疫学反应均为阴性。根据囊尾蚴在脑内的定位,观察到三组脑囊尾蚴病:水肿型、脑积水型和肿瘤型。这些类型及其症状与人类脑囊尾蚴病相似。

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