Flisser A, Tarrab R, Willms K, Larralde C
Arch Invest Med (Mex). 1975;6(1):1-12.
This paper describes the immune reactivity of the sera of humans with different probabilities of suffering cerebral cysticercosis as measured in immunoelectrophoresis and double diffusion against antigenic fractions from the wall, the liquid and the scolex of Cysticercus cellulosae. The proportion of positive sera with any antigenic fraction increased with the likelyhood of suffering cerebral cysticercosis, although some variation was found between antigenic fractions. Scolex and wall antigens showed the maximal discriminatory power between sick and healthy individuals: the probability of a false positive being less than 0.05 and that of a false negative ranging between 0.4 and 0.5. With these estimates it is concluded that a positive serum in immunoelectrophoresis or double diffusion against scolex or wall antigens practically establishes the diagnosis of cerebral cysticerocosis, although this event will occur in only half of the patients afflicted by the disease. The ease of execution of these tests and their discriminatory power between healthy and sick humans justify their establishment among diagnostic tools in cerebral cysticercosis.
本文描述了在免疫电泳和双向扩散中，针对猪囊尾蚴壁、囊液和头节的抗原成分，检测不同患脑囊尾蚴病概率人群血清的免疫反应性。尽管不同抗原成分之间存在一些差异，但对任何抗原成分呈阳性的血清比例会随着患脑囊尾蚴病可能性的增加而升高。头节和壁抗原在患病个体与健康个体之间显示出最大的鉴别能力：假阳性概率小于0.05，假阴性概率在0.4至0.5之间。根据这些评估结果得出结论，在免疫电泳或双向扩散中，针对头节或壁抗原呈阳性的血清实际上可确诊脑囊尾蚴病，尽管这种情况仅会出现在一半的患病患者中。这些检测操作简便，且在健康人与患病者之间具有鉴别能力，这证明它们可作为脑囊尾蚴病诊断工具。
