Goldman J K, Bernardis L L, Kodis M
Metabolism. 1978 Dec;27(12 Suppl 2):2006-8. doi: 10.1016/s0026-0495(78)80016-x.
Young male rats were injected with tritiated water 6 hr after destruction of the ventromedial hypothalamic nuclei (VMN). One hour later they were sacrificed and the incorporation of tritium into liver and carcass lipids, proteins, and glycogen and into plasma glucose and proteins was measured. It was found that lesioned rats showed increased incorporation into carcass and liver lipid, liver and plasma protein and plasma glucose. Conclusions are that the processes of lipogenesis and gluconeogenesis are accelerated within 6 hr after VMN destruction.
在破坏腹内侧下丘脑核（VMN）6小时后，给年轻雄性大鼠注射氚水。1小时后将它们处死，并测量氚掺入肝脏、胴体的脂质、蛋白质和糖原以及血浆葡萄糖和蛋白质中的情况。结果发现，受损大鼠的氚掺入胴体和肝脏脂质、肝脏和血浆蛋白质以及血浆葡萄糖中的量增加。结论是，在VMN破坏后6小时内，脂肪生成和糖异生过程加速。
