加拿大医院分离出的革兰氏阴性杆菌对氨基糖苷类抗生素的耐药性。
Resistance to aminoglycoside antibiotics of gram-negative bacilli isolated in Canadian hospitals.
作者信息
Duncan I B, Cheung E Y, Haldane E V, Jackson F L, McNaughton R D, Morisset R A, Noble M A, Rennie R P, Ronald A R, Smith J A
出版信息
Can Med Assoc J. 1981 May 1;124(9):1165-7.
A survey was made of the frequency of resistance to amikacin, gentamicin and tobramycin among aerobic gram-negative bacilli isolated over a 4-week period in 1979 at six large, geographically separated Canadian hospitals. In the entire series of 4407 isolates the frequency of resistance was 2.5% to amikacin, 8.1% to gentamicin, 5.9% to tobramycin and 1.7% to all three. Most (81%) of the resistant bacteria were acquired by the patients after admission to hospital. The frequency of resistance to the three aminoglycoside antibiotics in each hospital largely reflected the local rate of cross-infection by endemic strains of resistant bacteria.
对1979年在加拿大六家地理位置分散的大型医院，在四周时间内分离出的需氧革兰氏阴性杆菌对丁胺卡那霉素、庆大霉素和妥布霉素的耐药频率进行了一项调查。在总共4407株分离菌中，对丁胺卡那霉素的耐药频率为2.5%，对庆大霉素为8.1%，对妥布霉素为5.9%，对这三种抗生素均耐药的为1.7%。大多数（81%）耐药菌是患者入院后获得的。每家医院对这三种氨基糖苷类抗生素的耐药频率在很大程度上反映了当地耐药细菌流行菌株的交叉感染率。
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