Santidrian S, Sobrini F J, Bello J, Larralde J
Enzyme. 1981;26(2):103-6. doi: 10.1159/000459156.
A significant reduction (p less than 0.01) in both the rate of growth and liver protein was found in growing male rats fed ad libitum over a 5-week period on a diet containing raw field bean (Vicia faba L.) as the sole source of protein, as compared to casein-fed rats. The activity of the hepatic enzyme guanidinoacetate methyltransferase (EC 2.1.1.2) as well as the urinary output of total nitrogen and creatinine were also significantly increased (p less than 0.01) in the legume-fed rats. The addition of methionine to the legume diet did not improve the antinutritive effect caused by the raw field bean. The possible nature of these effects is discussed.
与喂食酪蛋白的大鼠相比，在5周时间内随意采食以生蚕豆（野豌豆）作为唯一蛋白质来源的日粮的生长雄性大鼠中，发现其生长速率和肝脏蛋白质均显著降低（p<0.01）。在喂食豆类的大鼠中，肝脏酶胍基乙酸甲基转移酶（EC 2.1.1.2）的活性以及总氮和肌酐的尿量也显著增加（p<0.01）。在豆类日粮中添加蛋氨酸并不能改善生蚕豆引起的抗营养作用。本文讨论了这些作用可能的性质。
