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Alterations in antigenic properties of normal epidermis adjacent to basal cell carcinomas.

作者信息

Wolf D, Bystryn J C

出版信息

J Invest Dermatol. 1981 Jun;76(6):442-4. doi: 10.1111/1523-1747.ep12521051.

DOI:10.1111/1523-1747.ep12521051
PMID:7240790
Abstract

The expression of U-CYT antigens, tissue-specific cytoplasmic antigens of keratinocytes that are markers of the terminal differentiation of these cells, was studied in normal skin adjacent to malignant epidermal tumors. Ten basal-cell carcinomas were studied. In all cases, it was found that the expression of U-CYT antigens in normal epidermis gradually decreased with increasing proximity to the tumors and finally disappeared completely within the tumor tissue itself. This finding suggests that basal-cell carcinoma can alter the normal differentiation of adjacent nonmalignant cells.

摘要

相似文献

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