Puffer H W, Beal M L
Lab Anim Sci. 1981 Apr;31(2):200-1.
California killifish (Fundulus parvipinnis) trapped in a Southern California estuary were infested with Gyrodactylus sp, Argulus sp, or Ergasilus sieboldii. They were treated with 0,0-dimethyl 2,2,2-trichloro-1-hydroxyethylphosphonate (DTHP). The effective dosage regimen for Gyrodactylus was 7.50 mg/l for 1 hour on day 1, 3.25 mg/l for 1 hour on day 5, and 0.75 mg/l for 1 hour on day 9; for Argulus, 2.50 mg/l for 1 hour once only; for Ergasilus, 2.50 mg/l for 1 hour once every third day for three treatments. Toxicity testing indicated that repetitive doses of 4.20 mg/l were toxic and that static exposures of more than 1 hour to doses of 7.50 mg/l were lethal to Fundulus.
被困在南加州河口的加利福尼亚鳉鱼(Fundulus parvipinnis)感染了三代虫属(Gyrodactylus sp)、鱼虱属(Argulus sp)或西氏鱼虱(Ergasilus sieboldii)。它们接受了0,0 - 二甲基2,2,2 - 三氯 - 1 - 羟乙基膦酸酯(DTHP)的治疗。三代虫的有效给药方案为第1天7.50毫克/升,持续1小时;第5天3.25毫克/升,持续1小时;第9天0.75毫克/升,持续1小时;鱼虱为2.50毫克/升,仅处理1次,持续1小时;鱼虱为2.50毫克/升,每三天处理1次,持续1小时,共处理三次。毒性测试表明,重复剂量4.20毫克/升具有毒性,而对剂量为7.50毫克/升的静态暴露超过1小时对加利福尼亚鳉鱼具有致死性。