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DNA-植物激素相互作用中的手性与立体化学识别:一种模型方法。

Chirality and stereochemical recognition in DNA-phytohormone interactions: a model approach.

作者信息

Witham F H, Hendry L B, Chapman O L

出版信息

Orig Life. 1978 Sep;9(1):7-15. doi: 10.1007/BF00929709.

DOI:10.1007/BF00929709
PMID:724246
Abstract

Space-filling molecular models of selected phytohormones and DNA, employed as described herein, illustrate possible in vivo stereochemical recognition between nucleic acids and intercalated phytohormones. In this regard, the absolute chirality of certain phytohormones, and that of DNA may be essential for the recognition process. It is speculated further that the specific interactions shown by molecular models have significance in the evolution of plant regulatory mechanisms.

摘要

本文所述的选定植物激素和DNA的空间填充分子模型,展示了核酸与嵌入的植物激素之间可能的体内立体化学识别。在这方面,某些植物激素的绝对手性以及DNA的绝对手性可能对识别过程至关重要。进一步推测,分子模型所示的特定相互作用在植物调节机制的进化中具有重要意义。

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1
Chirality and stereochemical recognition in DNA-phytohormone interactions: a model approach.DNA-植物激素相互作用中的手性与立体化学识别:一种模型方法。
Orig Life. 1978 Sep;9(1):7-15. doi: 10.1007/BF00929709.
2
Gene regulation: the involvement of stereochemical recognition in DNA-small molecule interactions.基因调控:立体化学识别在DNA与小分子相互作用中的参与
Perspect Biol Med. 1977 Autumn;21(1):120-30. doi: 10.1353/pbm.1977.0018.
3
Chirality as a tool in nucleic acid recognition: principles and relevance in biotechnology and in medicinal chemistry.手性作为核酸识别的一种工具:生物技术和药物化学中的原理及意义。
Chirality. 2007 May 5;19(4):269-94. doi: 10.1002/chir.20372.
4
Structural basis for the regulation of phytohormone receptors.植物激素受体调控的结构基础。
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Chiromers: conformation-driven mirror-image supramolecular chirality isomerism identified in a new class of helical rosette nanotubes.手性超分子:在一类新型螺旋冠醚纳米管中发现的构象驱动的手性镜像超分子手性异构体。
Nanoscale. 2014 Aug 21;6(16):9421-7. doi: 10.1039/c4nr00340c. Epub 2014 Apr 28.
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miRNAs in the crosstalk between phytohormone signalling pathways.植物激素信号通路间相互作用中的微小RNA
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Evolution of Hormone Signaling Networks in Plant Defense.植物防御中激素信号网络的演化。
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A quantitative measure of chirality inside nucleic acid databank.一种定量测量核酸数据库中手性的方法。
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本文引用的文献

1
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Separation and localization of two classes of auxin binding sites in corn coleoptile membranes.玉米中胚轴质膜上两类生长素结合位点的分离与定位。
基于由DNA模型构建的“腔”的拓扑结构和物理化学性质,对遗传密码进行立体化学原理的首次近似。
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4
Benzyl derivative facilitation of transcription in Escherichia coli at the ara and lac operon promoters: metabolite gene regulation (MGR).苄基衍生物对大肠杆菌中阿拉伯糖操纵子和乳糖操纵子启动子转录的促进作用:代谢物基因调控(MGR)
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Metabolite gene regulation of the L-arabinose operon in Escherichia coli with indoleacetic acid and other indole derivatives.吲哚乙酸及其他吲哚衍生物对大肠杆菌中L-阿拉伯糖操纵子的代谢物基因调控
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6
Metabolite gene regulation: imidazole and imidazole derivatives which circumvent cyclic adenosine 3',5'-monophosphate in induction of the Escherichia coli L-arabinose operon.代谢物基因调控:在大肠杆菌L-阿拉伯糖操纵子诱导过程中规避环磷酸腺苷的咪唑及咪唑衍生物。
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7
Are there structural analogies between amino acids and nucleic acids?氨基酸和核酸之间存在结构上的相似性吗?
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Planta. 1976 Jan;130(1):15-21. doi: 10.1007/BF00390839.
4
Auxin binding to corn coleoptile membranes: Kinetics and specificity.生长素与玉米胚芽鞘质膜的结合:动力学和特异性。
Planta. 1976 Jan;130(1):7-13. doi: 10.1007/BF00390838.
5
Cytokinins extracted from pinto bean fruit.从菜豆果实中提取的细胞分裂素。
Plant Physiol. 1971 Sep;48(3):320-4. doi: 10.1104/pp.48.3.320.
6
Interactions in vitro between gibberellins and DNA. II. Optical rotatory profile of the thermal denaturatin of DNA-gibberellin complexes.
Biochim Biophys Acta. 1971 Apr 8;232(4):611-3.
7
Cytokinin of wheat germ transfer RNA: 6-(4-hydroxy-3-methyl-2-butenylamino)-2-methylthio-9-beta-D-ribofuranosylpurine.小麦胚转移核糖核酸的细胞分裂素:6-(4-羟基-3-甲基-2-丁烯基氨基)-2-甲硫基-9-β-D-呋喃核糖基嘌呤。
Science. 1969 Dec 5;166(3910):1272-4. doi: 10.1126/science.166.3910.1272.
8
A protein intermediary in the interaction of a hormone with the genome.一种在激素与基因组相互作用中起中介作用的蛋白质。
Proc Natl Acad Sci U S A. 1969 Jul;63(3):897-903. doi: 10.1073/pnas.63.3.897.
9
Evidence for the natural occurrence of zeatin and derivatives: compounds from maize which promote cell division.玉米素及其衍生物自然存在的证据:来自玉米的促进细胞分裂的化合物。
Proc Natl Acad Sci U S A. 1965 Oct;54(4):1052-8. doi: 10.1073/pnas.54.4.1052.
10
Interactions in vitro between gibberellins and DNA.赤霉素与DNA的体外相互作用。
Biochim Biophys Acta. 1969 Nov 19;195(1):207-18. doi: 10.1016/0005-2787(69)90617-0.