通过微核试验对某些植物黄酮类化合物进行遗传毒理学研究。
Genetic toxicological of some plant flavonoids by the micronucleus test.
作者信息
Sahu R K, Basu R, Sharma A
出版信息
Mutat Res. 1981 May;89(1):69-74. doi: 10.1016/0165-1218(81)90132-4.
PMID:7242547
Abstract
4 important flavonoid compounds, namely quercetin, kaempferol, neohesperidin dihydrochalcone and rutin, were administered to male mice for the detection of gross chromosomal anomalies by the micronucleus test. The first 3 compounds were positively clastogenic to different extents, whereas the 4th was negative.
摘要
将4种重要的类黄酮化合物，即槲皮素、山奈酚、新橙皮苷二氢查耳酮和芦丁，给予雄性小鼠，通过微核试验检测染色体的总体异常情况。前3种化合物在不同程度上具有明显的致断裂性，而第4种则呈阴性。
Zotero 插件