Takase M, Saeki N, Oka N, Satoh A, Otaki M, Yamaura A
No Shinkei Geka. 1981;9(3):343-47.
The patient was a 48-year-old housewife, who had a sudden onset of severe headache followed by loss of consciousness for a few hours on the day of admission. Initially she showed slight restlessness due to headache, neck stiffness and subhyaloid hemorrhage. Four-vessel study revealed a basilar aneurysm on right retrograde brachial angiography and anterior communicating aneurysm on left carotid angiography. Two weeks after the onset, when she had no neurological deficit except for intermittent appearance of disorientation, both aneurysms were successfully clipped through right pterional approach of Yasargil. The subarachnoid hemorrhage was apparently due to basilar bifurcation aneurysm. Postoperatively, she showed right hemiparesis including her face, aniscocoria (left, 4 mm, oval: right, 1.5 mm, round) and conjugate deviation toward the left. The disturbance of conjugate eye movement and the hemiparesis completely disappeared in 2 and 7 days respectively. The patient was discharged 4 weeks postoperatively with mild left 3rd nerve palsy. At present, one year postoperatively, she is fully engaged in her housewife life without any neurological deficits. A case of superior Foville syndrome combined with Weber syndrome after clipping of basilar bifurcation aneurysm was reported and its anatomicoclinical mechanism was reviewed. The pathogenesis was supposed to be left midbrain ischemic lesion due to circulatory disturbance of P-1 perforators (P-1: proximal posterior cerebral artery); e.g., occlusion on clipping of vasospasm. This P-1 perforator syndrome after aneurysmal clipping has been reported only little. The importance of preservation of these perforators with careful dissection and manipulation under microscopy was emphasized.
患者为一名48岁的家庭主妇,入院当天突然出现剧烈头痛,随后意识丧失数小时。最初,她因头痛、颈部僵硬和玻璃体下出血而略显烦躁不安。四血管造影研究显示,右侧逆行肱动脉造影发现基底动脉瘤,左侧颈动脉造影发现前交通动脉瘤。发病两周后,除间歇性定向障碍外无神经功能缺损,通过Yasargil右侧翼点入路成功夹闭了两个动脉瘤。蛛网膜下腔出血显然是由基底动脉分叉处动脉瘤引起的。术后,她出现右侧偏瘫,包括面部、瞳孔不等大(左侧4mm,椭圆形;右侧1.5mm,圆形)以及向左的共轭偏斜。共轭眼球运动障碍和偏瘫分别在2天和7天内完全消失。患者术后4周出院,遗留轻度左侧动眼神经麻痹。目前,术后一年,她已完全恢复家庭主妇生活,无任何神经功能缺损。本文报告了一例基底动脉分叉处动脉瘤夹闭术后合并上Foville综合征和Weber综合征的病例,并对其解剖临床机制进行了回顾。发病机制推测为P-1穿支(P-1:大脑后动脉近端)循环障碍导致左侧中脑缺血性病变,例如夹闭时血管痉挛导致的闭塞。这种动脉瘤夹闭术后的P-1穿支综合征报道较少。强调了在显微镜下仔细解剖和操作以保留这些穿支的重要性。