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肝动脉栓塞术治疗肝脏肿瘤

Hepatic artery embolization in the treatment of hepatic neoplasms.

作者信息

Chuang V P, Wallace S

出版信息

Radiology. 1981 Jul;140(1):51-8. doi: 10.1148/radiology.140.1.7244243.

Abstract

Seventy-two hepatic artery embolizations were performed in 47 patients to treat hepatic neoplasms. Hepatic artery embolization creates tumor devascularization, but the portal flow prevents infarction of liver parenchyma because of the single vascular supply from the hepatic artery to a neoplasm, in contrast to the dual vascular supply to the liver parenchyma. Indications for the use of hepatic artery embolization are failure of chemotherapy, either systemic or intra-arterial infusion, vascular anomalies requiring combined lobar embolization and lobar infusion, and lack of effective treatment. Three types of embolization were performed: peripheral embolization using Gelfoam, proximal embolization using coils, and combined peripheral and proximal embolization. The complications after embolization were pain, fever, and transient liver function changes. No death or hepatic abscess occurred. The median survival duration of the group was 11.5 months from the time of embolization. Hepatic artery embolization is an effective treatment of hepatic neoplasm.

摘要

对47例患者进行了72次肝动脉栓塞术以治疗肝脏肿瘤。肝动脉栓塞可造成肿瘤缺血,但由于肿瘤仅由肝动脉单一供血,与肝实质的双重供血不同,门静脉血流可防止肝实质梗死。肝动脉栓塞术的应用指征包括全身或动脉内灌注化疗失败、需要联合叶栓塞和叶灌注的血管异常以及缺乏有效治疗方法。进行了三种类型的栓塞:使用明胶海绵的外周栓塞、使用弹簧圈的近端栓塞以及外周和近端联合栓塞。栓塞后的并发症包括疼痛、发热和短暂的肝功能改变。未发生死亡或肝脓肿。该组患者从栓塞时起的中位生存期为11.5个月。肝动脉栓塞术是治疗肝脏肿瘤的有效方法。

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