Romeo G, Sanfilippo G, Basile F, Catania G, Iannello A, Carnazza M L
Surg Gynecol Obstet. 1981 Jul;153(1):61-4.
The records of 16 patients of a total of 402 who underwent parietal cell vagotomy without a drainage procedure for duodenal ulcer were reviewed. Biopsies of gastric mucosa were taken before the operation and six months, two years and three years postoperatively. Ultrastructural studies using electron microscopy detail the modifications of the parietal cells which are the main target of the vagal denervation procedure. The parietal cells are greatly modified within six months after parietal cell vagotomy with a significant reduction of the secretory surface of the cells and a sharp increase of tubulovesicular formations regain their preoperative morphologic appearance after two to three years but not their secretory capacity.
对402例因十二指肠溃疡接受壁细胞迷走神经切断术且未行引流手术的患者中的16例患者的记录进行了回顾。在手术前以及术后6个月、2年和3年取胃黏膜活检。使用电子显微镜进行的超微结构研究详细描述了壁细胞的变化，壁细胞是迷走神经切断术的主要靶点。壁细胞在壁细胞迷走神经切断术后6个月内发生显著变化，细胞分泌表面显著减少，管状小泡结构急剧增加，在两到三年后恢复其术前形态外观，但分泌能力未恢复。
