Lynch T G, Wright C B, Miller E V, Slaymaker E E
Stroke. 1981 May-Jun;12(3):325-30. doi: 10.1161/01.str.12.3.325.
The cerebrovascular Doppler examination (CDE) and oculopneumoplethysmography (OPG-Gee) were compared in a single population group with no statistically significant difference found between the 2 studies. There appeared to be an advantage to combinant testing, for when the results of the 2 studies were concordant there was an accuracy of 94% and a false negative rate of 8%. Clinical correlation was available in 96% of the patients, providing adequate evidence to support the adjuvant role of non-invasive screening in the evaluation of symptomatic individuals. The percentage of false negative studies and the incidence of ulcerative disease make a diagnostic role impractical at present. For the asymptomatic individual, the diagnostic role of non-invasive screening seems justified. The false negative studies in the present series were confined to those vessels with 50-70% stenoses, which are difficult to assess angiographically and may be better characterized by hemodynamic evaluations.
在单一人群组中对脑血管多普勒检查（CDE）和眼气容积描记法（OPG - Gee）进行了比较，两项研究之间未发现统计学上的显著差异。联合检测似乎具有优势，因为当两项研究结果一致时，准确率为94%，假阴性率为8%。96%的患者有临床相关性，为支持非侵入性筛查在有症状个体评估中的辅助作用提供了充分证据。假阴性研究的百分比和溃疡性疾病的发生率使得目前其诊断作用不切实际。对于无症状个体，非侵入性筛查的诊断作用似乎是合理的。本系列中的假阴性研究仅限于那些狭窄程度为50 - 70%的血管，这些血管在血管造影中难以评估，通过血流动力学评估可能能更好地进行特征描述。
