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[含有禽白血病-肉瘤复合体gs抗原补体结合抗体的鸽血清的特性]

[Properties of pigeon sera containing complement-fixing antibodies to the gs-antigen of the avian leukosis-sarcoma complex].

作者信息

Zueva Iu N, Iakovleva L S, Denisova R A, Mazurenko N P

出版信息

Vopr Virusol. 1977 Jul-Aug(4):470-3.

PMID:72455
Abstract

Pigeons bearing tumors caused by the Schmidt-Ruppin strain of Rous sarcoma virus were used for withdrawing sera containing complement-fixing (CF) antibody to the gs-antigen of avian leukosis-sarcoma complex. In the course of this study it was found that some of these sera, while having a high titer of CF antibody to the gs-antigen of the tumor tissue, did not detect this antigen in chicken embryonal tissue and feather follicles. It is suggested that these sera distinguish different components of gs-antigen in the tumor tissue on the one hand and in the embryonal tissue and feather follicles on the other. There was a correlation in the detection or lack of gs-antigen in preparations of feather follicles and embryonal tissue with all the sera examined. Feather follicles may serve as a convenient source of gs-antigen in practical work.

摘要

携带由劳氏肉瘤病毒施密特 - 鲁平株引起肿瘤的鸽子被用于提取含有针对禽白血病 - 肉瘤复合体gs抗原的补体结合(CF)抗体的血清。在这项研究过程中发现,这些血清中的一些虽然对肿瘤组织的gs抗原有高滴度的CF抗体,但在鸡胚组织和毛囊中却检测不到这种抗原。这表明这些血清一方面能区分肿瘤组织中gs抗原的不同成分,另一方面能区分胚组织和毛囊中gs抗原的不同成分。在所检测的所有血清中,毛囊和胚组织制剂中gs抗原的检测情况或未检测情况之间存在相关性。在实际工作中,毛囊可能是gs抗原的便利来源。

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