甲泼尼龙冲击疗法治疗狼疮性肾炎
The treatment of lupus nephritis by methyl prednisolone pulse therapy.
作者信息
Dosa S, Cairns S A, Lawler W, Mallick N P, Slotki I N
出版信息
Postgrad Med J. 1978 Sep;54(635):628-32. doi: 10.1136/pgmj.54.635.628.
Abstract
Four patients with proliferative glomerulonephritis due to systemic lupus erythematosus were treated with intravenous methyl prednisolone 'pulse' therapy. In all, eight courses of therapy were given, three for acute oliguric renal failure; and on each occasion there was a good response to the treatment. Clinical, histological and immunological details of the patients are presented. The diagnosis, treatment, and monitoring of disease activity in lupus nephritis are discussed in the light of this experience.
摘要
4例因系统性红斑狼疮导致增生性肾小球肾炎的患者接受了静脉注射甲泼尼龙“冲击”疗法。总共进行了8个疗程的治疗，其中3个疗程用于治疗急性少尿性肾衰竭；每次治疗均取得了良好的反应。文中呈现了这些患者的临床、组织学和免疫学详细信息。并根据这一经验对狼疮性肾炎的诊断、治疗及疾病活动监测进行了讨论。
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The treatment of lupus nephritis by methyl prednisolone pulse therapy.甲泼尼龙冲击疗法治疗狼疮性肾炎
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