Mishaeva N P, Votiakov V I, Tarasenko A B
Zh Mikrobiol Epidemiol Immunobiol. 1981 Mar(3):35-9.
Hyperimmune serum with the high content of antibodies to the saliva of noninfected ticks when injected into vertebrates, induced the development of resistance preventing the ticks from sticking to the skin and satiation, thus reducing the number of blood-sucking ticks reaching satiation and decreasing the weight of satiated ticks; as a result, the productivity of female ticks decreased the the number of ticks sharply dropped. When ticks infected with tick-borne encephalitis virus parasitized on the animals immune against the saliva antigens of noninfected ticks, the virus titers in the blood of these animals were lower than in the controls, and no infection of ticks, formerly free of the virus, occurred.
将含有高浓度针对未感染蜱唾液抗体的超免疫血清注入脊椎动物后,可诱导产生抗性,阻止蜱附着于皮肤并吸血,从而减少达到饱腹状态的吸血蜱数量,并降低饱腹蜱的体重;结果,雌性蜱的繁殖力下降,蜱的数量急剧减少。当感染蜱传脑炎病毒的蜱寄生于对未感染蜱唾液抗原具有免疫力的动物身上时,这些动物血液中的病毒滴度低于对照组,并且以前未感染病毒的蜱也未发生感染。