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暴露于模拟海拔5000米(540百帕)环境35 - 40分钟的男性尿液中的糖胺聚糖和羟脯氨酸。

Glycosaminoglycans and hydroxyproline in the urine of men exposed for 35-40 minutes to a simulated altitude of 5000m (540 hPa).

作者信息

Mikołajczyk H, Golec L, Pach B

出版信息

Acta Physiol Pol. 1981 Jan-Feb;32(1):57-62.

PMID:7246207
Abstract

Total urine portions were collected from 31 pilots and candidates for pilots before hypobarism, during 35-40 minutes of hypobarism at a simulated altitude of 5000 m (540 hPa) and following hypobarism. The measured volume of urine portions and amounts of glycosaminoglycans (GAG) and hydroxyproline (Hp) were calculated in 30-minute periods before the test, during hypobaric test and following this test. The average urine volume during hypobarism and average amounts of GAG and Hp in the urine collected during this period were found to be significantly increased in comparison with similar quantities before hypobarism. After the hypobarism the average urine volume was still augmented, whereas the average amount of Hp was lower than before hypobarism. During hypobarism the volume of urine and the amount of GAG and Hp were significantly positively correlated.

摘要

在31名飞行员及飞行学员处于低气压环境前、在模拟海拔5000米(540百帕)的低气压环境中持续35 - 40分钟期间以及低气压环境结束后,收集其全部尿液样本。在测试前30分钟时段、低气压测试期间以及测试结束后,分别计算所收集尿液样本的测量体积、糖胺聚糖(GAG)含量和羟脯氨酸(Hp)含量。结果发现,与低气压环境前的相应数值相比,低气压环境期间的平均尿量以及此期间所收集尿液中GAG和Hp的平均含量均显著增加。低气压环境结束后,平均尿量仍有所增加,而Hp的平均含量低于低气压环境前。在低气压环境期间,尿量与GAG和Hp的含量呈显著正相关。

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