Mikolajczyk H, Krzemińska Z
Med Pr. 1977;28(3):229-34.
The volume of urine andurinary output of glycosaminoglycans (GAG) have been investigated daily during 8-hrs shift (5:00 a.m. to 1:00 p.m.) within five consecutive days (from Monday to friday) in 24 workers exposed to hand-transmitted vibrations (hand-formers) and in 20 control not exposed workers. Total amount of GAG was determined by carbazole reaction. The average 8-hrs volume of urine was significantly higher in hand-formers than in control workers. Total average 8-hrs volume of urine amounted to 550+/- +/-194 cc in hand-formers and 430+/-180 cc in control workers. The average 8-hrs urinary output of GAG was also higher in hand-formers than in control workers, but the difference was statistically significant in first, fourth and fifth day of investigation. The total 8-hrs output of GAG was in the average 4.34+/-1.86 mg in hand-formers and 3.38+/-1.44 in control workers with the difference significant at p less than 0.001. The results of the investigation suggest that vibration transmitted to the body could be accompanied by increased urinary output of some connective tissue components which might be of interest in evaluation of exposure.
在连续五天（从周一到周五）的8小时轮班期间（上午5点至下午1点），对24名接触手部传递振动的工人（手部劳动者）和20名未接触的对照工人，每天都对尿量和糖胺聚糖（GAG）的尿排出量进行了调查。GAG的总量通过咔唑反应测定。手部劳动者的平均8小时尿量显著高于对照工人。手部劳动者的平均8小时总尿量为550±194毫升，对照工人为430±180毫升。手部劳动者的平均8小时GAG尿排出量也高于对照工人，但在调查的第一天、第四天和第五天，差异具有统计学意义。手部劳动者的8小时GAG总排出量平均为4.34±1.86毫克，对照工人为3.38±1.44毫克，差异在p<0.001时具有显著性。调查结果表明，传递到身体的振动可能伴随着某些结缔组织成分尿排出量的增加，这在评估接触情况时可能是有意义的。
