Glycosylated serum protein and hemoglobin A1 levels to measure control of glycemia.

The value of glycosylated serum protein and glycosylated hemoglobin levels for estimating diabetic control was compared in 14 patients over 8 weeks during which glycemic control was improved. Glycosylated hemoglobin levels were not an effective indicator of improved glycemic control for the preceding 2 weeks; glycosylated serum protein values, however, accurately reflected alteration of mean glycemic levels 1 and 2 weeks after improvement of glycemic control. Both measurements were equally satisfactory after 8 weeks. In five patients glycosylated serum protein and glycosylated albumin values appeared equally effective in predicting glycemic control.