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[热那亚人群中破伤风毒素抗体的流行率与年龄和性别的关系]

[Prevalence of tetanus toxin antibodies in the population of Genoa in relation to age and sex].

作者信息

Gasparini R, Coppola R C, D'Aste E, Sigari G

出版信息

Boll Ist Sieroter Milan. 1980 Nov 30;59(5):418-23.

PMID:7248071
Abstract

Antitetanus toxin antibodies were measured, by means of the passive haemagglutination in the sera of 739 Genoese subjects, distributed in the following age classes: 1-5, 6-12, 13-20, 21-30, 31-40, 41-50, 51-60, 61-70 and greater than or equal to 71 years. It has been possible to verify that subjects of both sexes, aged less than 12 years, have high titer antibodies, particularly the female subjects show, in comparison with their male contemporaries, higher amounts of antitoxin. Besides the latter resulted at consolidated protection levels in 48% of the males, between 13 and 30 years, while for the male subjects, aged between 31 and 60 years this percentage dropped to 22 and, lastly, to 4 for those aged beyond 61 years. Furthermore for females older than 31 years, it was impossible, except exceptionally, to detect the presence of antibodies at titers greater than or equal to 0.1 I.U./ml.

摘要

通过被动血凝试验检测了739名热那亚受试者血清中的抗破伤风毒素抗体,这些受试者分布在以下年龄组:1 - 5岁、6 - 12岁、13 - 20岁、21 - 30岁、31 - 40岁、41 - 50岁、51 - 60岁、61 - 70岁以及大于或等于71岁。已证实,12岁以下的男女受试者均有高滴度抗体,特别是女性受试者与同龄男性相比,抗毒素含量更高。此外,13至30岁的男性中,48%的人抗体水平处于巩固的保护水平,而31至60岁的男性这一比例降至22%,最后,61岁以上的男性这一比例仅为4%。此外,对于31岁以上的女性,除了极少数情况外,无法检测到滴度大于或等于0.1 I.U./ml的抗体。

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