Barbee R A, Halonen M, Lebowitz M, Burrows B
J Allergy Clin Immunol. 1981 Aug;68(2):106-11. doi: 10.1016/0091-6749(81)90167-6.
The distribution of total serum IgE determined by the paper radioimmunosorbent test (PRIST) is examined in a large random stratified community population. Prior to logarithmic conversion the distribution of this immunoglobulin is not normal, with almost 40% of values below 20 IU/ml. A normal distribution occurs following such conversion, with a geometric mean value of 32.1 IU/ml. Both age and sex, in addition to atopic status, relate to IgE level. In both sexes highest levels occur among 6- to 14-year-olds, and males have higher levels than females at any given age. Women over age 75 yr have the lowest levels (geometric mean 9.2 IU/ml). Subjects with positive skin test results have several times the concentration of IgE as their nonatopic counterparts.
采用纸放射免疫吸附试验（PRIST）测定了一大群随机分层的社区人群血清总IgE的分布情况。在对数转换之前，这种免疫球蛋白的分布并不呈正态分布，近40%的值低于20 IU/ml。进行这种转换后呈正态分布，几何平均值为32.1 IU/ml。除特应性状态外，年龄和性别均与IgE水平有关。在两个性别中，6至14岁的人群IgE水平最高，在任何给定年龄，男性的水平都高于女性。75岁以上的女性IgE水平最低（几何平均值为9.2 IU/ml）。皮肤试验结果呈阳性的受试者其IgE浓度是无特应性受试者的数倍。
