Barbizet J, Duizabo P, Poirier J
Rev Neurol (Paris). 1978 Apr;134(4):241-53.
A report on a case of herpes encephalitis in a patient of particularly high intellectual level who was kept under observation for a period of 13 years. Anatomical examination of the brain demonstrated massive bilateral destruction of the limbic system. Having studied the higher functions of this patient for many months it was possible to establish interesting correlations relating to the role of the limbic system. It appears to be indispensable for the utilization of verbal, praxognosic, and conceptual information. Though this is still retained in the intact neocortex, mobilization of the information is possible only when stimuli arise from the exterior and for as long as they last. Spontaneous evocation of this data is, in fact, impossible, as is the stocking of new information. The limbic system, therefore, while not being the site of retention of memorised informations which is the role of the neocortex, appears to be a logic system. Which is indispensable for proper functioning of the memory machine.
一份关于一名智力水平极高的患者患疱疹性脑炎的病例报告，该患者被观察了13年。脑部解剖检查显示边缘系统出现大面积双侧破坏。经过数月对该患者高级功能的研究，得以建立与边缘系统作用相关的有趣关联。边缘系统对于言语、动作识别和概念信息的利用似乎不可或缺。尽管这些信息仍保留在完整的新皮层中，但只有当外部刺激出现并持续时，信息的调动才有可能。实际上，这些数据的自发唤起以及新信息的存储都是不可能的。因此，边缘系统虽然不是记忆信息的存储部位（这是新皮层的作用），但似乎是一个逻辑系统，对于记忆机制的正常运作不可或缺。
