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“伦德”病毒,一种与海鸟和蜱虫相关的类冠状病毒病原体。

"Runde" viurs, a coronavirus-like agent associated with seabirds and ticks.

作者信息

Traavik T, Mehl R, Kjeldsberg E

出版信息

Arch Virol. 1977;55(1-2):25-38. doi: 10.1007/BF01314476.

DOI:10.1007/BF01314476
PMID:72555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7087166/
Abstract

From 206 I. uriae collected in the seabird colonies at Runde, Norway, two identical virus strains demonstrating no antigenic relationships to major arbovirus groups were isolated. The new strains demonstrated a corona-virus like morphology, haemagglutinated chicken red cells and were sensitive to sodium desoxycholate. Multiplication with CPE was demonstrated in BHK 21/c13 and BSC-1 cells, and without CPE in Vero and GMK cell cultures. The mouse pathogenicity was relatively low. In gel precipitation three to five specific lines were seen. Precipitating antibodies have been found in seabird species commonly infested by I. uriae. The ecological cirucmstances of the isolates indicate an earlier unrecognized arbovirus circulating between seabirds and I. uriae. This corona-like virus has been tentatively termed Runde virus.

摘要

从挪威伦德海鸟聚居地采集的206份海鸟虱样本中,分离出了两种与主要虫媒病毒组无抗原关系的相同病毒株。新毒株呈现出类似冠状病毒的形态,能凝集鸡红细胞,且对脱氧胆酸钠敏感。在BHK 21/c13和BSC - 1细胞中可观察到伴有细胞病变效应(CPE)的增殖,而在Vero和GMK细胞培养物中无CPE。小鼠致病性相对较低。在凝胶沉淀试验中可见三到五条特异性条带。在通常被海鸟虱寄生的海鸟物种中发现了沉淀抗体。这些分离株的生态环境表明,一种此前未被识别的虫媒病毒在海鸟和海鸟虱之间传播。这种类冠状病毒暂被命名为伦德病毒。

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Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence.仓鼠细胞克隆的多瘤病毒转化——对影响细胞感受态的遗传因素的研究
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