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“坦迪”病毒——一种新的虫媒病毒,于1929年在乌兹别克苏维埃社会主义共和国和土库曼苏维埃社会主义共和国从亚洲璃眼蜱(Hyalomma asiaticum asiaticum Schulee et Schlottke)和铅灰璃眼蜱(Hyalomma plumbeum plumbeum Panzer,1796)中分离得到。

Virus "Tamdy"--a new arbovirus, isolated in the Uzbee S.S.R. and Turkmen S.S.R. from ticks Hyalomma asiaticum asiaticum Schulee et Schlottke, 1929, and Hyalomma plumbeum plumbeum Panzer, 1796.

作者信息

Lvov D K, Sidorova G A, Gromashevsky V L, Kurbanov M, Skvoztsova L M, Gofman Y P, Berezina L K, Klimenko S M, Zakharyan V A, Aristova V A, Neronov V M

出版信息

Arch Virol. 1976;51(1-2):15-21. doi: 10.1007/BF01317830.

Abstract

Eleven virus strains were isolated from ticks Hyalomma asiaticum asiaticum Schulce et Schlottke, 1929, and Hyalomma plumbeum plumbeum Panzer, 1796,collected in 1971-1974 in desert regions of the Uzbee S.S.R. and the Turkmen S.S.R. According to CF test the strains were closely related to each other and not antigenically connected with viruses from antigenic groups A, B, California, CHF-Congo, Bakau, Bunyamwera, Gajam, Kaisodi, Qalyub, Kemerovo, Quaranfil, Simbu, Turlock, Hughes, Uukuniemi, Tete and 21 ungrouped viruses isolated from ticks. The virus was named "Tamdy" after the place of isolation of a prototype strain LEIV-1308 Uz. The virus does not agglutinate goose erythrocytes, it is pathogenic for suckling mice and 3 weeks old mice by intracerebral infection. Replication of a virus with CPE in cell cultures--L, Rh, A1--and without CPE--in pig embryo kidney cell cultures--was demonstrated. According to ultrafiltration and electron microscope data the size of the virus is about 90 nm. It is rather sensitive to lipid solvents and is an RNA-virus. Morphologically the virus resembles the Bunyaviridae.

摘要

1971年至1974年期间,在乌兹别克苏维埃社会主义共和国和土库曼苏维埃社会主义共和国的沙漠地区采集了亚洲璃眼蜱(Hyalomma asiaticum asiaticum Schulce et Schlottke, 1929)和铅色璃眼蜱(Hyalomma plumbeum plumbeum Panzer, 1796),从中分离出11株病毒。根据补体结合试验,这些毒株彼此密切相关,在抗原性上与A、B、加利福尼亚、CHF - 刚果、巴考、布尼亚韦拉、加扬、凯索迪、卡柳卜、克麦罗沃、库拉恩菲尔、辛布、特洛克、休斯、乌昆耶米、泰特等抗原组的病毒以及从蜱中分离出的21种未分类病毒无抗原关联。该病毒以原型毒株LEIV - 1uz的分离地命名为“坦迪”。该病毒不凝集鹅红细胞,经脑内接种对乳鼠和3周龄小鼠具有致病性。在细胞培养物——L、Rh、A1——中可观察到病毒产生细胞病变效应(CPE),在猪胚肾细胞培养物中则不产生CPE。根据超滤和电子显微镜数据,该病毒大小约为90纳米。它对脂溶剂相当敏感,是一种RNA病毒。在形态上,该病毒类似于布尼亚病毒科。

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