Konstantinidis E, Markowski B, Ernst H
Strahlentherapie. 1981 Jun;157(6):375-80.
Sixty-one patients with lymph node metastases and occult primary tumor are reported. The patients were analyzed with respect to age and sex, as well as to the histologic diagnosis of the lymph nodes examined. In 24 of these patients, the primary tumor was found later; in 12 of these, not until autopsy. Site and histologic type of the lymph node metastases permit conclusions about the primary tumor. Treatment of the metastasis by surgery or irradiation ist indicated in order to hinder expansion and, in cases of late discovery of primary tumor, to take advantage of the remaining chances for a cure. The prognosis is unfavorable when the primary tumor remains undiscovered. In our patient group, the average survival time following confirmation of a lymph node metastasis was only 25 months. Lymph node metastases in the neck region are a special case. Here, the occult primary tumor ist sometimes cured in connection with surgery and/or irradiation of the cervical region.
报告了61例有淋巴结转移且原发肿瘤隐匿的患者。对这些患者进行了年龄、性别分析，以及对所检查淋巴结的组织学诊断分析。在其中24例患者中，原发肿瘤后来被发现；其中12例直到尸检时才发现。淋巴结转移的部位和组织学类型有助于推断原发肿瘤。建议通过手术或放疗治疗转移灶，以阻止其扩散，并且在原发肿瘤发现较晚的情况下，利用剩余的治愈机会。如果原发肿瘤一直未被发现，预后则不佳。在我们的患者组中，确诊淋巴结转移后的平均生存时间仅为25个月。颈部区域的淋巴结转移是一种特殊情况。在此，隐匿的原发肿瘤有时会在颈部区域进行手术和/或放疗时得到治愈。
