Rossi E C, Louis G, Bieber M, Zeller E A
Thromb Haemost. 1978 Aug 31;40(1):37-42.
Platelet MAO activity and the aggregation response to epinephrine, ADP, and collagen were measured in normal subjects. There was a direct correlation between the amount of platelet MAO activity and the per cent aggregation induced by 1 and 2 micrometer epinephrine. There were lesser correlations between platelet MAO and ADP or collagen-induced aggregation. These findings suggest that platelet MAO may play a role in determining the response of human platelets to epinephrine.
在正常受试者中测量了血小板单胺氧化酶(MAO)活性以及对肾上腺素、二磷酸腺苷(ADP)和胶原的聚集反应。血小板MAO活性水平与1和2微摩尔肾上腺素诱导的聚集百分比之间存在直接相关性。血小板MAO与ADP或胶原诱导的聚集之间的相关性较小。这些发现表明,血小板MAO可能在决定人类血小板对肾上腺素的反应中起作用。