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类风湿关节炎中淋巴细胞群体及其促有丝分裂活性与血清铜和免疫球蛋白水平的关系评估。

Evaluation of lymphocyte populations and their mitogenic activity in relation to serum copper and immunoglobulin levels in rheumatoid arthritis.

作者信息

Attia W M, Clark H W, Brown T M

出版信息

Ann Allergy. 1981 Aug;47(2):99-103.

PMID:7258747
Abstract

Purified mononuclear cells from the peripheral blood and sera from 30 patients with active rheumatoid arthritis (RA) were compared to the control or standard values in respect to the total number of B (EA) and T (E) rosette forming lymphocytes, their responsiveness to phytohemagglutinin (PHA) and pokeweed (PWM) mitogen, and serum immunoglobulins, (C3) complement and copper levels. The RA patients had significantly lower values for EA cells, PWM stimulation index, hemoglobin and hematocrit. Significantly higher values for serum copper and sedimentation rates were found. Relatively higher values for IgG, M, A and C3 were found in RA patients with lower values for E cells.

摘要

将30例活动期类风湿关节炎(RA)患者外周血中的纯化单核细胞和血清,与对照组或标准值进行比较,比较内容包括B(EA)和T(E)花环形成淋巴细胞的总数、它们对植物血凝素(PHA)和商陆(PWM)有丝分裂原的反应性,以及血清免疫球蛋白、(C3)补体和铜水平。RA患者的EA细胞、PWM刺激指数、血红蛋白和血细胞比容值显著较低。血清铜和血沉率显著较高。E细胞值较低的RA患者的IgG、M、A和C3值相对较高。

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1
Evaluation of lymphocyte populations and their mitogenic activity in relation to serum copper and immunoglobulin levels in rheumatoid arthritis.类风湿关节炎中淋巴细胞群体及其促有丝分裂活性与血清铜和免疫球蛋白水平的关系评估。
Ann Allergy. 1981 Aug;47(2):99-103.
2
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Allerg Immunol (Leipz). 1976;22(2):147-58.
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[Lymphocyte responsiveness in the peripheral blood to nonspecific mitogens and the TH and TS lymphocyte subpopulation in progressive polyarthritis].[外周血淋巴细胞对非特异性有丝分裂原的反应性以及进行性多关节炎中的TH和TS淋巴细胞亚群]
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[Lymphocyte response to mitogens in serum-free and serum-containing medium in patients with rheumatoid arthritis (author's transl)].类风湿性关节炎患者在无血清和含血清培养基中对促细胞分裂剂的淋巴细胞反应(作者译)
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