Dossetor J F
Arch Dis Child. 1981 May;56(5):394-7. doi: 10.1136/adc.56.5.394.
A child who presented at age 9 months with steatorrhoea and malnutrition is described. After an initial period of intravenous feeding it was found that oral gentamicin led to a reduction of clinical steatorrhoea and an increase in weight, and so gentamicin was continued for 18 months. Investigation showed severe villous atrophy without pronounced inflammatory cell infiltrate and with no increase in intraepithelial lymphocytes. The villous atrophy was not present in the duodenum but started in the jejunum. The small-intestine was radiologically dilated throughout its length. It is suggested that this structurally-abnormal gut acted as a stagnant loop and exacerbated the steatorrhoea.
本文描述了一名9个月大出现脂肪泻和营养不良的儿童。在最初一段时间的静脉喂养后，发现口服庆大霉素可减轻临床脂肪泻并使体重增加，因此持续使用庆大霉素18个月。检查显示严重的绒毛萎缩，无明显炎性细胞浸润，上皮内淋巴细胞未增加。十二指肠未出现绒毛萎缩，而空肠开始出现。小肠在影像学上显示全段扩张。提示这种结构异常的肠道起到了停滞环的作用，加剧了脂肪泻。
