小鼠皮肤过敏反应的应变和性别依赖性敏感性。
Strain and sex dependent sensitivity to skin anaphylactic reactions in the mouse.
作者信息
Brzezińska-Błaszczyk E, Andrzejewska M, Kubicka M
出版信息
Arch Immunol Ther Exp (Warsz). 1980;28(6):869-72.
PMID:7259456
Abstract
The strain-dependent variation in sensitivity of mouse skin to passive cutaneous anaphylaxis (PCA) was observed. The results showed that this variation is not connected either with mast cell number and histamine content in the skin of different mouse strains or with the concentration of non-specific IgE on skin mast cells of these strains. Thus, other factors determining the susceptibility of mouse strains to PCA must exist.
摘要
观察到小鼠皮肤对被动皮肤过敏反应（PCA）的敏感性存在品系依赖性变化。结果表明，这种变化与不同小鼠品系皮肤中的肥大细胞数量和组胺含量均无关，也与这些品系皮肤肥大细胞上非特异性IgE的浓度无关。因此，必定存在其他决定小鼠品系对PCA易感性的因素。
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