组胺对正常人及白血病患者淋巴细胞E及EAC玫瑰花结形成的影响。
Effect of histamine on E and EAC rosettes formation of normal and leukemic human lymphocytes.
作者信息
Błasińska M J, Jodłowska E
出版信息
Arch Immunol Ther Exp (Warsz). 1980;28(6):895-9.
PMID:7259458
Abstract
Histamine at 10(-6) M inhibited E and increased EAC rosette formation of normal human peripheral lymphocytes. Cimetidine at 10(-3) M prevented the decrease in number of E rosette-forming cells. In CLL no influence of Hi on both E and EAC rosette formation was detected. In the light of these findings the presence of histamine receptor on human normal and leukemic lymphocytes is discussed.
摘要
10⁻⁶M的组胺抑制正常人外周淋巴细胞的E花环形成并增加EAC花环形成。10⁻³M的西咪替丁可防止E花环形成细胞数量减少。在慢性淋巴细胞白血病中，未检测到组胺对E花环和EAC花环形成有任何影响。根据这些发现，讨论了人正常淋巴细胞和白血病淋巴细胞上组胺受体的存在情况。
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