Alekseev V S, Kashpur A M
Ukr Biokhim Zh (1978). 1978 Sep-Oct;50(5):547-50.
When studying formation of pyruvic and lactic acids from fructose diphosphate the effect of dilution is found in the process of muscles homogenate incubation. Pyruvic acid accumulates only in samples with magnesium chloride added. The increase of lactic acid remains constant irrespectively of availability of conditions for pyruvate formation. Phosphoglycerate and phosphoenolpyruvate form pyruvic acid only in samples with magnesium chloride added without forming lactic acid. It is shown that in the muscles diluted homogenate (25 mg per 6 ml of mixture) lactic acid is formed under conditions unsuitable for pyruvic acid formation. Lactic acid is formed omitting the stages of 2-phosphoglycerate, phosphoenolpyruvate and pyruvate i.e. in the pathway different from a classical scheme of glycolysis.
在研究由二磷酸果糖形成丙酮酸和乳酸的过程中，在肌肉匀浆孵育过程中发现了稀释的影响。丙酮酸仅在添加了氯化镁的样品中积累。无论丙酮酸形成的条件如何，乳酸的增加都保持恒定。磷酸甘油酸和磷酸烯醇丙酮酸仅在添加了氯化镁的样品中形成丙酮酸，而不形成乳酸。结果表明，在稀释的肌肉匀浆（每6毫升混合物25毫克）中，乳酸是在不适合丙酮酸形成的条件下形成的。乳酸的形成省略了2-磷酸甘油酸、磷酸烯醇丙酮酸和丙酮酸的阶段，即在不同于经典糖酵解途径的途径中形成。
