Alekseev V S, Kashpur A M, Gorozhanskaia E G, Misiuk N M, Klopotskiĭ G A
Vopr Med Khim. 1977 Mar-Apr;23(2):185-7.
Effect of MgCl2 and ATP on the elevation in lactate, pyruvate and methylglyoxale content was studied on incubation of fructosediphosphate with muscle and tumor homogenates. Muscle homogenate accumulated lactate, pyruvate and methyglyoxale more intensively as compared with tumor homogenate. Pyruvate was formed only in presence of MgCl2 and ATP, although it did not practically affect the elevation of lactate in muscle homogenate. The data obtained suggest that tumor homogenate does not contain the enzymatic system involved in methylglyoxale formation.
通过将磷酸果糖与肌肉和肿瘤匀浆一起孵育，研究了氯化镁和三磷酸腺苷（ATP）对乳酸、丙酮酸和甲基乙二醛含量升高的影响。与肿瘤匀浆相比，肌肉匀浆更强烈地积累乳酸、丙酮酸和甲基乙二醛。丙酮酸仅在氯化镁和ATP存在的情况下形成，尽管它实际上对肌肉匀浆中乳酸的升高没有影响。所获得的数据表明，肿瘤匀浆不含有参与甲基乙二醛形成的酶系统。
