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Mechanism of reaction of carcinogen N-acetoxy-2-acetylaminofluorene with DNA.

作者信息

Bobst A M, Wang T V, Cerutti P A

出版信息

Experientia. 1981 Jun;37(6):597-8. doi: 10.1007/BF01990071.

DOI:10.1007/BF01990071
PMID:7262287
Abstract
摘要

相似文献

1
Mechanism of reaction of carcinogen N-acetoxy-2-acetylaminofluorene with DNA.
Experientia. 1981 Jun;37(6):597-8. doi: 10.1007/BF01990071.
2
C-alkylation of N-acetoxy-N-2-acetylaminofluorene: effects on its reaction with DNA in vitro.N-乙酰氧基-N-2-乙酰氨基芴的C-烷基化:对其体外与DNA反应的影响
Cancer Biochem Biophys. 1984 Jun;7(2):89-99.
3
DNA binding spectrum of the carcinogen N-acetoxy-N-2-acetylaminofluorene significantly differs from the mutation spectrum.致癌物N-乙酰氧基-N-2-乙酰氨基芴的DNA结合谱与突变谱显著不同。
J Mol Biol. 1984 Jul 25;177(1):173-80. doi: 10.1016/0022-2836(84)90063-9.
4
An ultimate chemical carcinogen, N-acetoxy-2-acetylaminofluorene, detects non-B DNA structures that are reactive with chloroacetaldehyde in supercoiled plasmid DNA.一种终极化学致癌物,N-乙酰氧基-2-乙酰氨基芴,可检测超螺旋质粒DNA中与氯乙醛反应的非B型DNA结构。
Carcinogenesis. 1988 Mar;9(3):457-61. doi: 10.1093/carcin/9.3.457.
5
Reactivity of B and Z-DNA towards N-acetoxy-2-acetylaminofluorene.B型和Z型DNA对N-乙酰氧基-2-乙酰氨基芴的反应活性。
Nucleic Acids Res. 1982 Jul 24;10(14):4423-30. doi: 10.1093/nar/10.14.4423.
6
Preferential reaction of the carcinogen N-acetoxy-2-acetylaminofluorene with satellite DNA.致癌物N-乙酰氧基-2-乙酰氨基芴与卫星DNA的优先反应。
Chem Biol Interact. 1984 Apr;49(1-2):177-87. doi: 10.1016/0009-2797(84)90060-7.
7
DNA adduct formation and removal in N-acetoxy-2-acetylaminofluorene-exposed cultured cells and in organs from rats fed 2-acetylaminofluorene.在暴露于N-乙酰氧基-2-乙酰氨基芴的培养细胞以及喂食2-乙酰氨基芴的大鼠器官中DNA加合物的形成与去除
Basic Life Sci. 1983;24:619-35. doi: 10.1007/978-1-4684-4400-1_33.
8
An ELISA for detection of DNA-bound carcinogen using a monoclonal antibody to N-acetoxy-2-acetylaminofluorene-modified DNA.
J Immunol Methods. 1987 Apr 16;98(2):195-200. doi: 10.1016/0022-1759(87)90005-6.
9
The reproducibility of individual estimations in the covalent binding of N-acetoxy-2-acetylaminofluorene to DNA and in the induction of unscheduled DNA synthesis.N-乙酰氧基-2-乙酰氨基芴与DNA共价结合以及诱导非预定DNA合成过程中个体评估的可重复性。
Mutat Res. 1983 Jun;120(4):219-24. doi: 10.1016/0165-7992(83)90093-3.
10
Electron microscopic visualization of N-acetoxy-N-2-acetylaminofluorene binding sites in ColE1 DNA by means of specific antibodies.通过特异性抗体对ColE1 DNA中N-乙酰氧基-N-2-乙酰氨基芴结合位点进行电子显微镜观察。
Proc Natl Acad Sci U S A. 1979 Dec;76(12):6076-80. doi: 10.1073/pnas.76.12.6076.

本文引用的文献

1
Arylamidation and arylation by the carcinogen N-2-fluorenylacetamide: a sensitive and rapid radiochemical assay.致癌物N-2-芴基乙酰胺引发的芳酰胺化和芳基化反应:一种灵敏且快速的放射化学分析方法。
Anal Biochem. 1978 Dec;91(2):663-73. doi: 10.1016/0003-2697(78)90553-5.
2
Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification.聚乙二醇存在下噬菌体的快速沉降及其在大规模病毒纯化中的应用
Virology. 1970 Mar;40(3):734-44. doi: 10.1016/0042-6822(70)90218-7.
3
Reactions of esters of N-hydroxy-2-acetamidophenanthrene with cellular nucleophiles and the formation of free radicals upon decomposition of N-acetoxy-N-arylacetamides.
N-羟基-2-乙酰氨基菲的酯与细胞亲核试剂的反应以及N-乙酰氧基-N-芳基乙酰胺分解时自由基的形成。
Cancer Res. 1973 Jun;33(6):1159-64.
4
Carcinogenesis by aromatic amines.芳香胺致癌作用
Biochim Biophys Acta. 1974 Sep 9;355(2):177-203. doi: 10.1016/0304-419x(74)90003-1.
5
Differential excision from DNA of the C-8 and N2 guanosine adducts of N-acetyl-2-aminofluorene by single strand-specific endonucleases.利用单链特异性核酸内切酶从DNA中差异切除N-乙酰-2-氨基芴的C-8和N2鸟苷加合物。
Cancer Res. 1977 Oct;37(10):3756-60.
6
Reactivity of the antibodies to DNA modified by the carcinogen N-acetoxy-N-acetyl-2-aminofluorene.抗体对由致癌物N-乙酰氧基-N-乙酰基-2-氨基芴修饰的DNA的反应性。
Biochemistry. 1979 Apr 3;18(7):1328-32. doi: 10.1021/bi00574a032.
7
Excision repair of benzo[a]pyrene-deoxyguanosine adducts in baby hamster kidney 21/C13 cells and in secondary mouse embryo fibroblasts C57BL/6J.在幼仓鼠肾21/C13细胞和二代小鼠胚胎成纤维细胞C57BL/6J中苯并[a]芘-脱氧鸟苷加合物的切除修复
Proc Natl Acad Sci U S A. 1977 Mar;74(3):979-83. doi: 10.1073/pnas.74.3.979.