Exponential model for a two-ligand, regulatory enzyme. Part 2: Performance tests of the 'INDEXP' computer program for the determination of model constants from initial velocity data. I. Artificial data.
作者信息
Ainsworth S, Gregory R B, Kinderlerer J
出版信息
Int J Biomed Comput. 1981 Jul;12(4):315-34. doi: 10.1016/0020-7101(81)90043-x.
PMID:7263100
Abstract
The exponential model for a regulatory enzyme describes the relationship between the initial velocity of the catalysed reaction and the concentration of two ligands. A program, entitled 'INDEXP' has been designed to analyse rate data in terms of the model (Kinderlerer et at., 1981) and, in this report, its performance is examined when presented with artificial data generated from known constants and random, normally distributed error. It is shown that 'INDEXP' is able to recover good estimates of the constants.
摘要
相似文献
1
Exponential model for a two-ligand, regulatory enzyme. Part 2: Performance tests of the 'INDEXP' computer program for the determination of model constants from initial velocity data. I. Artificial data.
Int J Biomed Comput. 1981 Jul;12(4):315-34. doi: 10.1016/0020-7101(81)90043-x.
2
Exponential model for a two-ligand, regulatory enzyme. Part 3: Performance tests of INDEXP computer programs for determination of model constants from initial velocity data. 2. Experimental data.
Int J Biomed Comput. 1981 Jul;12(4):335-48. doi: 10.1016/0020-7101(81)90044-1.
3
Exponential model for a two-ligand, regulatory enzyme. Part 1: computer programs for the determination of the model constants from initial velocity data.双配体调节酶的指数模型。第1部分：根据初始速度数据确定模型常数的计算机程序。
Int J Biomed Comput. 1981 Jul;12(4):291-313. doi: 10.1016/0020-7101(81)90042-8.
4
The exponential model for a regulatory enzyme: a computer program to determine the constants for the binding of a single ligand.
Int J Biomed Comput. 1979 Jan;10(1):29-36. doi: 10.1016/0020-7101(79)90040-0.
5
Location of critical points in the reaction velocity/concentration relationships predicted by the exponential model for a two substrate regulatory enzyme.双底物调节酶指数模型预测的反应速度/浓度关系中关键点的位置。
Int J Biomed Comput. 1984 Jul-Aug;15(4):249-58. doi: 10.1016/0020-7101(84)90061-8.
6
Exponential model for a regulatory enzyme. Computer program for the determination of the model constants from initial velocity data.调节酶的指数模型。用于根据初速度数据确定模型常数的计算机程序。
Int J Biomed Comput. 1987 Mar;20(3):163-73. doi: 10.1016/0020-7101(87)90026-2.
7
A computer program to derive the rate equations of enzyme catalysed reactions with up to ten enzyme-containing intermediates in the reaction mechanism.
Int J Biomed Comput. 1976 Jan;7(1):1-20. doi: 10.1016/0020-7101(76)90002-7.
8
The effect of pH on enzyme-catalysed reactions: a computer program to determine pK values of enzyme ionisable groups from kinetic data.pH对酶催化反应的影响：一个根据动力学数据确定酶可电离基团pK值的计算机程序。
Int J Biomed Comput. 1980 Jan;11(1):53-66. doi: 10.1016/0020-7101(80)90006-9.
9
Determination of initial velocities of enzymic reactions from progress curves.根据反应进程曲线测定酶促反应的初速度
Biochem J. 1986 Aug 1;237(3):821-5. doi: 10.1042/bj2370821.
10
The derivation of second degree rate equations arising from two-substrate, two-product enzyme catalysed reactions whose catalytic cycle is branched.由催化循环呈分支状的双底物、双产物酶催化反应产生的二级速率方程的推导。
Int J Biomed Comput. 1976 Apr;7(2):119-29. doi: 10.1016/0020-7101(76)90011-8.
引用本文的文献
1
The regulatory properties of rabbit muscle pyruvate kinase. The influence of substrate concentrations.兔肌丙酮酸激酶的调节特性。底物浓度的影响。
Biochem J. 1983 Feb 1;209(2):401-11. doi: 10.1042/bj2090401.
Zotero 插件