Swahn C H, Sedvall G
J Neurochem. 1981 Aug;37(2):461-6. doi: 10.1111/j.1471-4159.1981.tb00478.x.
The presence of tele-methylhistamine in human cerebrospinal fluid has been established. The concentration was determined with the use of deuterated tele-methylhistamine. The preparation of the deuterated standard is described. The concentration range in samples from neuropsychiatric patients was 0.1--2.5 ng/ml. The structure of the pentafluoropropionyl derivative used for gas chromatography was studied with the aid of proton nuclear magnetic resonance spectroscopy.
已证实人体脑脊液中存在间甲基组胺。使用氘代间甲基组胺测定其浓度。描述了氘代标准品的制备方法。神经精神疾病患者样本中的浓度范围为0.1 - 2.5 ng/ml。借助质子核磁共振光谱研究了用于气相色谱的五氟丙酰衍生物的结构。
