Silva O L, Titus-Dillon P, Becker K L, Snider R H, Moore C F
J Natl Med Assoc. 1981;73(7):649-52.
Calcitonin, the hypocalcemic, hypophosphatemic polypeptide hormone of C cell origin, has been reported to be high in pregnant women at delivery. Levels of this hormone were determined by radioimmunoassay in 56 pregnant women in all trimesters and found to be above normal in 72 percent. Values were also increased during the first two days postpartum. Calcitonin levels were not correlated with serum calcium or phosphate, except in the first trimester when levels of this hormone were inversely correlated with serum phosphate. Perhaps the hypercalcitonemia of pregnancy serves to protect the maternal skeleton, while allowing the fetus to accumulate calcium.
降钙素是一种由C细胞产生的具有降血钙、降血磷作用的多肽激素,据报道,孕妇分娩时其水平较高。采用放射免疫分析法测定了56例处于妊娠各期的孕妇体内该激素的水平,发现72%的孕妇该激素水平高于正常。产后前两天其值也有所升高。降钙素水平与血清钙或磷无相关性,但在妊娠早期该激素水平与血清磷呈负相关。也许妊娠期间的高降钙素血症有助于保护母体骨骼,同时使胎儿能够积累钙。