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孕期血清降钙素升高。

Increased serum calcitonin in pregnancy.

作者信息

Silva O L, Titus-Dillon P, Becker K L, Snider R H, Moore C F

出版信息

J Natl Med Assoc. 1981;73(7):649-52.

PMID:7265273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2553013/
Abstract

Calcitonin, the hypocalcemic, hypophosphatemic polypeptide hormone of C cell origin, has been reported to be high in pregnant women at delivery. Levels of this hormone were determined by radioimmunoassay in 56 pregnant women in all trimesters and found to be above normal in 72 percent. Values were also increased during the first two days postpartum. Calcitonin levels were not correlated with serum calcium or phosphate, except in the first trimester when levels of this hormone were inversely correlated with serum phosphate. Perhaps the hypercalcitonemia of pregnancy serves to protect the maternal skeleton, while allowing the fetus to accumulate calcium.

摘要

降钙素是一种由C细胞产生的具有降血钙、降血磷作用的多肽激素,据报道,孕妇分娩时其水平较高。采用放射免疫分析法测定了56例处于妊娠各期的孕妇体内该激素的水平,发现72%的孕妇该激素水平高于正常。产后前两天其值也有所升高。降钙素水平与血清钙或磷无相关性,但在妊娠早期该激素水平与血清磷呈负相关。也许妊娠期间的高降钙素血症有助于保护母体骨骼,同时使胎儿能够积累钙。

相似文献

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Increased serum calcitonin in pregnancy.孕期血清降钙素升高。
J Natl Med Assoc. 1981;73(7):649-52.
2
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6
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Co-expression of the calcitonin receptor gene in the hypothalamic kisspeptin neurons in female rats.降钙素受体基因在雌性大鼠下丘脑促性腺激素释放激素神经元中的共表达。 (注:原文中“kisspeptin neurons”翻译有误,正确的是“gonadotropin-releasing hormone neurons”,即促性腺激素释放激素神经元,按照正确内容翻译的译文如上,供你参考,若按你提供的错误原文翻译为:降钙素受体基因在雌性大鼠下丘脑亲吻素神经元中的共表达 )
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Effects of pregnancy and lactation on bone mineral density, and their relation to the serum calcium, phosphorus, calcitonin and parathyroid hormone levels in rats.妊娠和哺乳期对大鼠骨矿物质密度的影响及其与血清钙、磷、降钙素和甲状旁腺激素水平的关系。
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本文引用的文献

1
Determination of calcium in blood serum by atomic absorption spectroscopy.用原子吸收光谱法测定血清中的钙
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Determination of serum ionic calcium with an ion-selective electrode: evaluation of methodology and normal values.
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Calcium metabolism in normal human pregnancy.正常人类妊娠中的钙代谢
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4
A suggested physiological role of calcitonin: the protection of the skeleton during pregnancy and lactation.降钙素的一种推测性生理作用:在妊娠和哺乳期对骨骼的保护作用。
J Endocrinol. 1971 Mar;49(3):ix-x.
5
[Estrogens and calcitonin].[雌激素与降钙素]
Nouv Presse Med. 1972 Jul 1;1(27):1845-6.
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Physiologic hyperparathyroidism in pregnancy.妊娠期生理性甲状旁腺功能亢进
J Clin Endocrinol Metab. 1972 May;34(5):767-71. doi: 10.1210/jcem-34-5-767.
7
A radioimmunoassay for ovine calcitonin: an evaluation of calcitonin secretion during gestation, lactation and foetal life.一种用于绵羊降钙素的放射免疫分析:对妊娠、泌乳和胎儿期降钙素分泌的评估。
J Endocrinol. 1974 Sep;62(3):497-509. doi: 10.1677/joe.0.0620497.
8
Plasma calcitonin-like activity and urinary cyclic adenosine monophosphate during pregnancy, parturition, and lactation in cows with parturient hypocalcemia.分娩期低钙血症奶牛在妊娠、分娩和泌乳期间的血浆降钙素样活性及尿环磷酸腺苷
Horm Metab Res. 1973 Jul;5(4):297-302. doi: 10.1055/s-0028-1093932.
9
Radioimmunoassay of calcitonin in human plasma.人血浆中降钙素的放射免疫测定
Clin Chem. 1974 Mar;20(3):337-9.
10
Calcium balance in pregnancy.孕期钙平衡
Lancet. 1974 Oct 19;2(7886):926-7. doi: 10.1016/s0140-6736(74)91132-5.