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J Natl Med Assoc. 1981 Aug;73(8):707-9.
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本文引用的文献

1
Human T lymphocyte receptors for sheep erythrocytes: conditions for binding including inhibition by cytochalasin B.人类对绵羊红细胞的T淋巴细胞受体:结合条件,包括细胞松弛素B的抑制作用。
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Effect of vinblastine on the early events in the humoral immune response of mice to SRBC.长春碱对小鼠针对绵羊红细胞的体液免疫应答早期事件的影响。
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Antitumor activity of deacetyl vinblastine amide sulfate (vindesine) in rodents and mitotic accumulation studies in culture.硫酸去乙酰长春花碱酰胺(长春地辛)在啮齿动物中的抗肿瘤活性及培养中的有丝分裂积累研究。
Cancer Res. 1978 Sep;38(9):2886-91.
4
Differential effect of vinblastine and colchicine on human active and total T rosettes.长春花碱和秋水仙碱对人活性和总T玫瑰花结的不同作用。
Int Arch Allergy Appl Immunol. 1977;55(1-6):148-51. doi: 10.1159/000231921.
5
Drugs which disrupt microtubules do not inhibit the initiation of lymphocyte activation.破坏微管的药物并不抑制淋巴细胞激活的起始。
Nature. 1977 Jan 27;265(5592):349-51. doi: 10.1038/265349a0.

长春花生物碱对小鼠抗绵羊红细胞抗体反应的免疫增强作用。

Immunopotentiating effect of vinca alkaloids on the antibody response to sheep red blood cells in the mouse.

作者信息

Byrd J R, Isa A M

出版信息

J Natl Med Assoc. 1981 Aug;73(8):707-9.

PMID:7265281
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2552687/
Abstract

Evidence is presented that the vinca alkaloids (vinblastine, vincristine, and vindesine) exert an immunopotentiating effect on the antibody response to sheep red blood cells (SRBC). The primary antibody response, measured by the rosette-forming cell (RFC) and hemagglutination (HA) assays, was enhanced by vincristine and vindesine treatments. Neither drug had any effect on the secondary antibody response. Vinblastine, while having no effect on the primary response, augmented the secondary antibody response to SRBC.

摘要

有证据表明,长春花生物碱(长春碱、长春新碱和长春地辛)对针对绵羊红细胞(SRBC)的抗体反应具有免疫增强作用。通过玫瑰花结形成细胞(RFC)和血凝(HA)试验测定的初次抗体反应,在接受长春新碱和长春地辛治疗后得到增强。两种药物对二次抗体反应均无影响。长春碱虽然对初次反应没有影响,但增强了对SRBC的二次抗体反应。