Kraus J F, Mull R, Kurtz P, Winterlin W, Franti C E, Kilgore W, Borhani N O
J Toxicol Environ Health. 1981 Jan;7(1):19-31. doi: 10.1080/15287398109529955.
This report describes the results of a long-term monitoring study of 36 grape harvesters who were occupationally exposed to organophosphate pesticide residues following reentry into vineyards during September and October 1976. The study was designed to evaluate biochemical parameters associated with organophosphate pesticide residues. Insignificant changes in blood cholinesterase activity were found. Some workers had very low levels of organophosphate metabolites in the urine during the entire 6 wk of study. Ethion dioxon was the only pesticide residue detected on the grape leaves. The harvesting of wine grapes involves numerous work crews of four to six people each, requiring a highly mobile monitoring staff. A single stationary location for collecting blood and urine samples will result in massive losses to follow-up since the workers cannot be relied on to report on their own. It is recommended that, to maximize worker cooperation, future monitoring studies rely more on analyses of urine specimens and less on venipuncture for evidence of pesticide exposure.
本报告描述了一项针对36名葡萄采摘工人的长期监测研究结果，这些工人于1976年9月和10月重新进入葡萄园后职业性接触有机磷农药残留。该研究旨在评估与有机磷农药残留相关的生化参数。研究发现血液胆碱酯酶活性变化不显著。在整个6周的研究期间，一些工人尿液中的有机磷代谢物水平非常低。乙硫磷二氧是在葡萄叶上检测到的唯一农药残留。酿酒葡萄的采摘涉及众多每组四到六人的工作团队，这需要一支高度流动的监测人员队伍。由于不能指望工人们自行报告，单一固定地点采集血液和尿液样本会导致大量失访。建议为了最大限度地提高工人的合作度，未来的监测研究更多地依赖尿液标本分析，而较少依赖静脉穿刺来获取农药暴露的证据。
