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[亲子鉴定中的触珠蛋白亚型]

[Haptoglobin subtypes in paternity cases].

作者信息

Menczer G

出版信息

Morphol Igazsagugyi Orv Sz. 1980 Jan;20(1):54-8.

PMID:7266497
Abstract

A brief review of theoretical and practical problems of the identification of haptoglobins (Hp) is given. Examination of Hp-subtypes was carried out in 335 cases of discussed paternity using polyacrylamide gel electrophoresis. According to the results of the examination of the sera of 285 adults (included into the above mentioned group) the gen frequency appeared to be as follows: when the frequency of the gen Hp1 = 0.346, the value of the frequency of Hp1F = 0.115 and Hp1S = 0.231. Thus the maximal (theoretical) chance of the exclusion of the paternity have been found 26.24%. Two cases are reported. In one of them determination of the Hp-subtypes resulted in exclusion of the discussed paternity.

摘要

本文简要回顾了触珠蛋白(Hp)鉴定的理论和实际问题。采用聚丙烯酰胺凝胶电泳法,对335例有争议的亲子鉴定案例进行了Hp亚型检测。根据对上述285名成年人血清的检测结果,基因频率如下:当基因Hp1的频率为0.346时,Hp1F的频率值为0.115,Hp1S的频率值为0.231。因此,排除亲子关系的最大(理论)概率为26.24%。报告了两个案例。其中一个案例中,Hp亚型的测定结果排除了有争议的亲子关系。

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