Martin J
Parasitology. 1981 Aug;83(Pt 1):43-50. doi: 10.1017/s0031182000050022.
Acetylcholinesterase (AChE) activity was measured in Nippostrongylus brasiliensis recovered during the course of a primary infection in normal and in protein-deficient rats. In well-nourished rats the amount of AChE present in N. brasiliensis increased as the infection progressed, concomitant with the development of the humoral response. In malnourished rats, there was a similar and parallel increase in the amount of AChE synthesized by worms between days 7 and 13 of the infection but as the infection progressed enzyme production decreased so that, by day 26 of the infection, the nematodes contained approximately the same amount of AChE as 8-day-old worms. The possible reasons for this change in enzyme production are discussed.
在正常和蛋白质缺乏的大鼠初次感染巴西日圆线虫的过程中，对回收的该线虫进行了乙酰胆碱酯酶（AChE）活性测定。在营养良好的大鼠中，随着感染的进展，巴西日圆线虫中AChE的含量增加，这与体液免疫反应的发展相伴。在营养不良的大鼠中，感染第7天至13天期间，线虫合成的AChE量有类似且平行的增加，但随着感染的进展，酶产量下降，以至于到感染第26天时，线虫所含的AChE量与8日龄线虫大致相同。文中讨论了酶产量这种变化的可能原因。
